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TRKB Antikörper (pTyr705)
NTRK2
Reaktivität: Human, Ratte, Maus
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5689749
Produktdetails anti-TRKB Antikörper
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Target
Alle TRKB (NTRK2) Antikörper anzeigen
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Bindungsspezifität
Alle Epitope für TRKB Antikörper
pTyr705
Reaktivität
Alle Reaktivitäten für TRKB Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für TRKB Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TRKB Antikörper
Polyklonal
Konjugat
Alle Konjugate für TRKB Antikörper
Dieser TRKB Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TRKB Antikörper
Western Blotting (WB)
Spezifität
This antibody detects endogenous level of TrkB only when phosphorylated at tyrosine 705.
Aufreinigung
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Immunogen
TrkB (Phospho-Tyr705) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 705 (T-D-Y P-Y-R) derived from Human TrkB.
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Alternativen
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 57-70), (Extracellular Domain) antibody
NTRK2
Reaktivität: Human, Ratte, Maus
WB, IHC, IF, FACS, ICC, LCI
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Western Blot: 1:500~1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store antibody at -20°C for up to one year.
Details zu TRKB
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Target
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Andere Bezeichnung
TrkB (NTRK2 Produkte )
Synonyme
trkb antikoerper, trkb-b antikoerper, xtrkb antikoerper, si:ch211-220b11.1 antikoerper, trkB2 antikoerper, NTRK2 antikoerper, ntrk2 antikoerper, gp145-trkb antikoerper, TRKB antikoerper, GP145-TrkB antikoerper, trk-B antikoerper, AI848316 antikoerper, C030027L06Rik antikoerper, Tkrb antikoerper, trkB antikoerper, RATTRKB1 antikoerper, TRKB1 antikoerper, Trk-B antikoerper, TrkB antikoerper, neurotrophic receptor tyrosine kinase 2 antikoerper, neurotrophic receptor tyrosine kinase 2 L homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2b antikoerper, neurotrophic receptor tyrosine kinase 2 S homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2 antikoerper, NTRK2 antikoerper, ntrk2.L antikoerper, ntrk2b antikoerper, ntrk2.S antikoerper, ntrk2 antikoerper, Ntrk2 antikoerper
Hintergrund
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC γ,1.
Molekulargewicht
140 kDa
Gen-ID
4915
NCBI Accession
NP_001007098
UniProt
Q16620
Pathways
RTK Signalweg , Neurotrophin Signalübertragung , cAMP Metabolic Process , Skeletal Muscle Fiber Development , Feeding Behaviour , Dicarboxylic Acid Transport
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