NFKB2 Antikörper (AA 864-868)

Produktnummer ABIN5689598

Produktdetails anti-NFKB2 Antikörper

Target: NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))

Bindungsspezifität: AA 864-868

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFKB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Spezifität: This antibody detects endogenous level of total NFκ,B-p100/p52 protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: NFkB-p100/p52 (Ab-866) antibody was raised against a peptide sequence around aa.864~868 (E-D-S-A-Y) derived from Human NFκ,B-p100/p52.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu NFKB2

Target: NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))

Andere Bezeichnung: NFkB p100 / p52 (NFKB2 Produkte)

Synonyme: NF-kappaB2 antikoerper, lyt antikoerper, p49 antikoerper, p49/p100 antikoerper, p50B antikoerper, p52 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antikoerper, Nfkb2 antikoerper

Hintergrund: NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ,-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ,-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

Molekulargewicht: 120 kDa

Gen-ID: 4791

NCBI Accession: NP_001070961

UniProt: Q00653

Pathways: Toll-Like Receptors Cascades