NFKB2 Antikörper (C-Term)

Produktnummer ABIN2854310

Produktdetails anti-NFKB2 Antikörper

Target: NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFKB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Spezifität: GTX101150 specifically recognizes NFkB p100 isoform, but not the cleaved p52 isoform.

Produktmerkmale: Rabbit Polyclonal antibody to NFkB p100 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 2)
NFkB p100 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human NFkB p100. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Kommentare:

Positive Control: A431 , HeLa , HepG2 , NIH-3T3 , *YY-8103

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NFKB2

Target: NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))

Andere Bezeichnung: NFkB p100 (NFKB2 Produkte)

Synonyme: NF-kappaB2 antikoerper, lyt antikoerper, p49 antikoerper, p49/p100 antikoerper, p50B antikoerper, p52 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antikoerper, Nfkb2 antikoerper

Hintergrund: NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].[supplied by OMIM]

Cellular Localization: Nucleus , Cytoplasm

Molekulargewicht: 97 kDa

Gen-ID: 4791

Pathways: Toll-Like Receptors Cascades