×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
PRKAA1 Antikörper (AA 485-489)
PRKAA1
Reaktivität: Human, Maus, Ratte
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5689419
Produktdetails anti-PRKAA1 Antikörper
(ausblenden)
Target
Alle PRKAA1 Antikörper anzeigen
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Bindungsspezifität
Alle Epitope für PRKAA1 Antikörper
AA 485-489
Reaktivität
Alle Reaktivitäten für PRKAA1 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für PRKAA1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PRKAA1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PRKAA1 Antikörper
Dieser PRKAA1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PRKAA1 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Spezifität
This antibody detects endogenous level of total AMPKα,1 protein.
Aufreinigung
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
AMPKa1 (Ab-487) antibody was raised in was raised against a peptide sequence around aa.485~489 (S-G-S-V-S) derived from Human AMPKα,1.
Top Product
Discover our top product PRKAA1 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Konzentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store antibody at -20°C for up to one year.
Details zu PRKAA1
(ausblenden)
Target
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Andere Bezeichnung
AMPKa1 (PRKAA1 Produkte )
Synonyme
AMPK antikoerper, AMPKa1 antikoerper, cb116 antikoerper, im:7154392 antikoerper, sb:cb130 antikoerper, wu:fa94c10 antikoerper, AMPK1 antikoerper, AMPKalpha1 antikoerper, AI194361 antikoerper, AI450832 antikoerper, AL024255 antikoerper, C130083N04Rik antikoerper, ampk antikoerper, ampka1 antikoerper, PRKAA1 antikoerper, protein kinase AMP-activated catalytic subunit alpha 1 antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antikoerper, PRKAA1 antikoerper, prkaa1 antikoerper, Prkaa1 antikoerper, prkaa1.L antikoerper
Hintergrund
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Molekulargewicht
63 kDa
Gen-ID
5562
NCBI Accession
NP_006242
UniProt
Q13131 , P54646
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effekt
Zuletzt angesehen
(ausblenden)