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DDX58 Antikörper (AA 201-713) (Biotin)

DDX58 Reaktivität: Human, Maus WB, IHC, IP Wirt: Maus Monoclonal Alme-1 Biotin
Produktnummer ABIN5688368
  • Target Alle DDX58 Antikörper anzeigen
    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-713
    Reaktivität
    • 65
    • 42
    • 17
    • 2
    • 1
    Human, Maus
    Wirt
    • 59
    • 9
    • 1
    • 1
    Maus
    Klonalität
    • 61
    • 9
    Monoklonal
    Konjugat
    • 37
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser DDX58 Antikörper ist konjugiert mit Biotin
    Applikation
    • 61
    • 19
    • 14
    • 14
    • 14
    • 11
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Spezifität
    Recognizes human and mouse RIG-I.
    Reinheit
    > 95% (SDS-PAGE)
    Immunogen
    Recombinant human RIG-I (aa 201-713).
    Klon
    Alme-1
    Isotyp
    IgG1
    Top Product
    Discover our top product DDX58 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry: (paraffin sections). Immunoprecipitation: (1:200). Western blot: (1:1,000).
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Liquid. In PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Stable for at least 1 year after receipt when stored at -20°C.
  • Target
    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
    Andere Bezeichnung
    RIG-I (DDX58 Produkte)
    Synonyme
    RIG-I antikoerper, RIGI antikoerper, RLR-1 antikoerper, 6430573D20Rik antikoerper, C330021E21 antikoerper, RHIV-1 antikoerper, RIG-1 antikoerper, DExD/H-box helicase 58 antikoerper, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 antikoerper, DEXD/H-box helicase 58 antikoerper, DDX58 antikoerper, Ddx58 antikoerper
    Hintergrund
    RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
    Gen-ID
    23586
    UniProt
    O95786
    Pathways
    Activation of Innate immune Response, Hepatitis C
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