AIMP1 Antikörper

Produktnummer ABIN5687576

Produktdetails anti-AIMP1 Antikörper

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser AIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Anti-hEMAP-II specific antibody was purified by affinity chromatography employing immobilized hEMAP-II matrix.

Immunogen: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hEMAP-II (human EMAP-II).

Anwendungsinformationen

Applikationshinweise: ELISA:

To detect hEMAP-II by direct ELISA (using 100 μ,L/well antibody solution) a concentration of at least 0.5 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hEMAP-II.

Sandwich: To detect hEMAP-II by sandwich ELISA (using 100 μ,L/well antibody solution) a concentration of 0.5 - 2.0 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human EMAP-II (XP-5122Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hEMAP-II.

Western Blot:

To detect hEMAP-II by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hEMAP-II is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Lagerung: -20 °C

Informationen zur Lagerung: EMAP-II antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.

Details zu AIMP1

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Andere Bezeichnung: EMAP-II (AIMP1 Produkte)

Synonyme: EMAP2 antikoerper, EMAPII antikoerper, HLD3 antikoerper, SCYE1 antikoerper, p43 antikoerper, wu:fa95a05 antikoerper, zgc:154081 antikoerper, AIMP1 antikoerper, 9830137A06Rik antikoerper, AIMP1/p43 antikoerper, Emap2 antikoerper, Scye1 antikoerper, scye1 antikoerper, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog antikoerper, AIMP1 antikoerper, aimp1 antikoerper, Aimp1 antikoerper, aimp1.S antikoerper

Hintergrund: EMAP II is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor associated vasculature sensitive to tumor necrosis factor. Its precursor is identical to the p43 subunit, which is associated with the multi tRNA synthetase complex. Therefore, proEMAP II may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. EMAP II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.

Gen-ID: 9255

UniProt: Q12904