PSMB7 Antikörper (Internal Region)

Produktnummer ABIN568708

Produktdetails anti-PSMB7 Antikörper

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PSMB7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-RNAVLEADFA KR

Spezifität: Recognizes PSMB7.

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Cow, Pig.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002790.1. Genename: PSMB7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PSMB7

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Andere Bezeichnung: PSMB7 (PSMB7 Produkte)

Synonyme: DDBDRAFT_0185624 antikoerper, DDBDRAFT_0232933 antikoerper, DDB_0185624 antikoerper, DDB_0232933 antikoerper, AU020723 antikoerper, MC14 antikoerper, Z antikoerper, 20S proteasome subunit beta-7 antikoerper, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog antikoerper, proteasome subunit beta 7 antikoerper, proteasome (prosome, macropain) subunit, beta type, 7 antikoerper, proteasome (prosome, macropain) subunit, beta type 7 antikoerper, psmB7 antikoerper, psmb7.S antikoerper, PSMB7 antikoerper, Psmb7 antikoerper

Hintergrund: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).Synonyms: Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome 20S beta 7, Proteasome subunit Z, Proteasome subunit beta type-7

Gen-ID: 5695

NCBI Accession: NP_002790

UniProt: Q99436

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA