CIRBP Antikörper (Internal Region)

Produktnummer ABIN568701

Produktdetails anti-CIRBP Antikörper

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Bindungsspezifität: AA 81-91, Internal Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CIRBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-QAGKSSDNRS R

Spezifität: Recognizes CIRBP (aa 81-91).

Kreuzreaktivität (Details): Species reactivity (expected):Human, Dog, Cow.
Species reactivity (tested):Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001271.1. Genename: CIRBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CIRBP

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Andere Bezeichnung: CIRBP (CIRBP Produkte)

Synonyme: CIRP antikoerper, Cirp antikoerper, R74941 antikoerper, Xcirp antikoerper, cirbp antikoerper, cirbp-a antikoerper, cirbp2 antikoerper, cirp antikoerper, cirp1 antikoerper, cirp2 antikoerper, xcirp2 antikoerper, XCIRP antikoerper, XCIRP-1 antikoerper, cirbp-b antikoerper, cirp-1 antikoerper, APBP-1 antikoerper, zgc:136559 antikoerper, CIRBP antikoerper, A18 hnRNP antikoerper, cold inducible RNA binding protein antikoerper, cold-inducible RNA-binding protein antikoerper, cold inducible RNA binding protein S homeolog antikoerper, cold inducible RNA binding protein L homeolog antikoerper, cold inducible RNA binding protein b antikoerper, CIRBP antikoerper, EDI_107320 antikoerper, Cirbp antikoerper, cirbp.S antikoerper, cirbp.L antikoerper, cirbp antikoerper, cirbpb antikoerper

Hintergrund: CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature.Synonyms: A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP

Gen-ID: 1153

NCBI Accession: NP_001271

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization