PLAUR Antikörper (AA 23-305)

Produktnummer ABIN5663892

Produktdetails anti-PLAUR Antikörper

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Bindungsspezifität: AA 23-305

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAUR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRCMQCKTNG DCRVEECALG QDLCRTTIVR LWEEGEELEL VEKSCTHSEK TNRTLSYRTG LKITSLTEVV CGLDLCNQGN SGRAVTYSRS RYLECISCGS SDMSCERGRH QSLQCRSPEE QCLDVVTHWI QEGEEGRPKD DRHLRGCGYL PGCPGSNGFH NNDTFHFLKC CNTTKCNEGP ILELENLPQN GRQCYSCKGN STHGCSSEET FLIDCRGPMN QCLVATGTHE PKNQSYMVRG CATASMCQHA HLGDAFSMNH IDVSCCTKSG CNHPDLDVQY RSG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-305 of human PLAUR (NP_002650.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Andere Bezeichnung: PLAUR (PLAUR Produkte)

Synonyme: Cd87 antikoerper, u-PAR antikoerper, uPAR antikoerper, CD87 antikoerper, U-PAR antikoerper, UPAR antikoerper, URKR antikoerper, Par antikoerper, Plaur3 antikoerper, uPAR-2 antikoerper, uPAR-3 antikoerper, PLAUR antikoerper, plasminogen activator, urokinase receptor antikoerper, Plaur antikoerper, PLAUR antikoerper

Hintergrund: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.,PLAUR,CD87,U-PAR,UPAR,URKR,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Extracellular Matrix,Immunology & Inflammation,CD markers,Cardiovascular,Blood,PLAUR

Molekulargewicht: 31 kDa/32 kDa/36 kDa

Gen-ID: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process