PLAUR Antikörper (AA 23-305)

Produktnummer ABIN7193215

Produktdetails anti-PLAUR Antikörper

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Bindungsspezifität: AA 23-305

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLAUR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CD87 (AA: 23-305) expressed in E. coli.

Klon: 1D1B11

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Andere Bezeichnung: CD87 (PLAUR Produkte)

Synonyme: Cd87 antikoerper, u-PAR antikoerper, uPAR antikoerper, CD87 antikoerper, U-PAR antikoerper, UPAR antikoerper, URKR antikoerper, Par antikoerper, Plaur3 antikoerper, uPAR-2 antikoerper, uPAR-3 antikoerper, PLAUR antikoerper, plasminogen activator, urokinase receptor antikoerper, Plaur antikoerper, PLAUR antikoerper

Hintergrund:

Description: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Aliases: PLAUR, UPAR, URKR, U-PAR

Molekulargewicht: 37 kDa

Gen-ID: 5329

Pathways: Inositol Metabolic Process