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SAV1 Antikörper (AA 300-383)

SAV1 Reaktivität: Human WB, ELISA, IF, IP Wirt: Maus Monoclonal 3B2 unconjugated
Produktnummer ABIN566210
  • Target Alle SAV1 Antikörper anzeigen
    SAV1 (Salvador Homolog 1 (SAV1))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 300-383
    Reaktivität
    • 30
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    • 5
    • 1
    Maus
    Klonalität
    • 29
    • 2
    Monoklonal
    Konjugat
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SAV1 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 18
    • 7
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Verwendungszweck
    Mouse monoclonal antibody raised against a partial recombinant SAV1.
    Sequenz
    HTAEIPDWLQ VYARAPVKYD HILKWELFQL ADLDTYQGML KLLFMKELEQ IVKMYEAYRQ ALLTELENRK QRQQWYAQQH GKNF
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    SAV1 (NP_068590, 300 a.a. ~ 383 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    3B2
    Isotyp
    IgG2a
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kai, Tsukamoto, Hijiya, Tokunaga, Nakada, Uchida, Daa, Iha, Takahashi, Nomura, Sato, Mimata, Ikawa, Seto, Matsuura, Moriyama: "Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway." in: The Journal of pathology, Vol. 239, Issue 1, pp. 97-108, (2016) (PubMed).

    Schütte, Bisht, Heukamp, Kebschull, Florin, Haarmann, Hoffmann, Bendas, Buettner, Brossart, Feldmann: "Hippo signaling mediates proliferation, invasiveness, and metastatic potential of clear cell renal cell carcinoma." in: Translational oncology, Vol. 7, Issue 2, pp. 309-21, (2014) (PubMed).

    Park, Kim, Won, Jeon, Oh, Lee, Kim, Lee: "Mammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPAR?." in: PLoS ONE, Vol. 7, Issue 1, pp. e30983, (2012) (PubMed).

    Li, Luo, Li, Wang, Xiao, Tao, Gong, Hu: "Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system." in: Molecular biology reports, Vol. 39, Issue 8, pp. 8225-30, (2012) (PubMed).

    Murakami, Mizuno, Taniguchi, Fujii, Ishiguro, Fukui, Akatsuka, Horio, Hida, Kondo, Toyokuni, Osada, Sekido: "LATS2 is a tumor suppressor gene of malignant mesothelioma." in: Cancer research, Vol. 71, Issue 3, pp. 873-83, (2011) (PubMed).

    Mardin, Lange, Baxter, Hardy, Scholz, Fry, Schiebel: "Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction." in: Nature cell biology, Vol. 12, Issue 12, pp. 1166-76, (2010) (PubMed).

  • Target
    SAV1 (Salvador Homolog 1 (SAV1))
    Andere Bezeichnung
    SAV1 (SAV1 Produkte)
    Synonyme
    SAV antikoerper, WW45 antikoerper, WWP4 antikoerper, 1700040G09Rik antikoerper, Salv antikoerper, Sav antikoerper, Wwp3 antikoerper, Wwp4 antikoerper, salvador family WW domain containing protein 1 antikoerper, salvador family WW domain containing 1 antikoerper, SAV1 antikoerper, Sav1 antikoerper
    Hintergrund
    Full Gene Name: salvador homolog 1 (Drosophila)
    Synonyms: SAV,WW45,WWP4
    Gen-ID
    60485
    NCBI Accession
    NM_021818
    Pathways
    Stem Cell Maintenance
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