STT3A Antikörper (AA 476-507)

Produktnummer ABIN5647816

Produktdetails anti-STT3A Antikörper

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Bindungsspezifität: AA 476-507

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STT3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität (Details): Expected species reactivity: Mouse,Bovine

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 476-507 from the human protein was used as the immunogen for the STT3A antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1:1000-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the STT3A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu STT3A

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Andere Bezeichnung: STT3A (STT3A Produkte)

Synonyme: cb437 antikoerper, wu:fb38c11 antikoerper, AA408947 antikoerper, BB081708 antikoerper, Itm1 antikoerper, ITM1 antikoerper, STT3-A antikoerper, TMC antikoerper, STT3A, subunit of the oligosaccharyltransferase complex (catalytic) antikoerper, STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) antikoerper, STT3A, catalytic subunit of the oligosaccharyltransferase complex antikoerper, stt3a antikoerper, Stt3a antikoerper, STT3A antikoerper

Hintergrund: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A is the catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

Gen-ID: 3703

UniProt: P46977