STT3A Antikörper (AA 476-507)

Produktnummer ABIN6243748

Produktdetails anti-STT3A Antikörper

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Bindungsspezifität: AA 476-507

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STT3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STT3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 476-507 amino acids from the Central region of human STT3A.

Klon: RB56284

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu STT3A

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Andere Bezeichnung: STT3A (STT3A Produkte)

Synonyme: cb437 antikoerper, wu:fb38c11 antikoerper, AA408947 antikoerper, BB081708 antikoerper, Itm1 antikoerper, ITM1 antikoerper, STT3-A antikoerper, TMC antikoerper, STT3A, subunit of the oligosaccharyltransferase complex (catalytic) antikoerper, STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) antikoerper, STT3A, catalytic subunit of the oligosaccharyltransferase complex antikoerper, stt3a antikoerper, Stt3a antikoerper, STT3A antikoerper

Hintergrund: Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

Molekulargewicht: 80530

UniProt: P46977