CD147 Antikörper

Produktnummer ABIN5647740

Produktdetails anti-CD147 Antikörper

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD147 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids E138-A323 from the human protein were used as the immunogen for the Basigin / CD147 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD147 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Basigin / CD147 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: CD147 / Emmprin / Basigin (BSG Produkte)

Synonyme: EMMPRIN antikoerper, RPE7 antikoerper, 5F7 antikoerper, CD147 antikoerper, M6 antikoerper, OK antikoerper, TCSF antikoerper, AI115436 antikoerper, AI325119 antikoerper, HT-7 antikoerper, 5A11 antikoerper, CE9 antikoerper, HT7 antikoerper, Ox47R antikoerper, basignin antikoerper, wu:fb26a05 antikoerper, wu:fo98e12 antikoerper, bsg antikoerper, prso03 antikoerper, basigin (Ok blood group) antikoerper, basigin antikoerper, basigin (Ok blood group) S homeolog antikoerper, BSG antikoerper, Bsg antikoerper, bsg antikoerper, bsg.S antikoerper

Hintergrund: Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG, Basigin) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. The human gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. Basigin has been shown to be an essential receptor on red blood cells for the malaria parasite. It is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily, it plays fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development. BSG is thought also to play a role in intercellular recognition. It also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. BSG is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.

UniProt: P35613

Pathways: S100 Proteine