CD147 Antikörper
Kurzübersicht für CD147 Antikörper (ABIN7234142)
Target
Alle CD147 (BSG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen Affinity Purification
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Immunogen
- Recombinant Rat Basigin protein
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-1:2000 IHC 1:100-1:300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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Andere Bezeichnung
- BSG
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Hintergrund
- BSG,also named as 5F7,Basigin,EMMPRIN,TCSF and CD147,plays pivotal roles in spermatogenesis,embryo implantation,neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1,SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA,inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix,plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
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Molekulargewicht
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Observed_MW: 30 kDa,40-60 kDa
Calculated_MW: 30 kDa,40-60 kDa
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UniProt
- P26453
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Pathways
- S100 Proteine
Target
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