Optimal dilution of the ABCC1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the ABCC1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
ABCC1
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
ABC29 antikoerper, ABCC antikoerper, GS-X antikoerper, MRP antikoerper, MRP1 antikoerper, Abcc1a antikoerper, Abcc1b antikoerper, Mdrap antikoerper, Mrp1 antikoerper, Avcc1a antikoerper, Mrp antikoerper, ABCC13 antikoerper, ATP binding cassette subfamily C member 1 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 1 antikoerper, multidrug resistance-associated protein 1 antikoerper, ABCC1 antikoerper, Abcc1 antikoerper, LOC100152428 antikoerper, LOC100346553 antikoerper
Hintergrund
Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.