NCR3 Antikörper (AA 31-65)

Produktnummer ABIN5647395

Produktdetails anti-NCR3 Antikörper

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Bindungsspezifität: AA 31-65

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 31-65 from the N-terminal region of the human protein was used as the immunogen for the NKp30 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the NKp30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western Blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NKp30 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Andere Bezeichnung: NKp30 / NCR3 (NCR3 Produkte)

Synonyme: MGC133750 antikoerper, 1C7 antikoerper, CD337 antikoerper, LY117 antikoerper, MALS antikoerper, NKp30 antikoerper, Nkp30 antikoerper, natural cytotoxicity triggering receptor 3 antikoerper, NCR3 antikoerper, Ncr3 antikoerper

Hintergrund: Natural cytotoxicity triggering receptor 3 (NCR3), also called Natural killer cell p30-related protein (NKp30), is a cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process