NCR3 Antikörper (AA 31-65)
Kurzübersicht für NCR3 Antikörper (AA 31-65) (ABIN6242894)
Target
Alle NCR3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 31-65
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Homologie
- H
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This NCR3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-65 amino acids from the human region of human NCR3.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
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Andere Bezeichnung
- NCR3
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Hintergrund
- Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
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Molekulargewicht
- 21593
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UniProt
- O14931
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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