XRN1 Antikörper (AA 1455-1706)

Produktnummer ABIN5647152

Produktdetails anti-XRN1 Antikörper

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Bindungsspezifität: AA 1455-1706

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XRN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: A human recombinant protein corresponding to amino acids 1455-1706 was used as the immunogen for the XRN1 antibody.

Klon: 1647CT536-85-48

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Western blot: 1:1000-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the XRN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Andere Bezeichnung: XRN1 (XRN1 Produkte)

Synonyme: wu:fk92c07 antikoerper, zgc:63635 antikoerper, SEP1 antikoerper, Dhm2 antikoerper, exo antikoerper, mXrn1 antikoerper, RGD1309713 antikoerper, 5'-3' exoribonuclease 1 antikoerper, xrn1 antikoerper, XRN1 antikoerper, Tsp_05930 antikoerper, Xrn1 antikoerper

Hintergrund: 5'-3' Exoribonuclease 1 is a major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Gen-ID: 54464

UniProt: Q8IZH2