CLEC1B
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Substanzklasse
Viral Protein
Hintergrund
Natural killer (NK) cells express multiple C-type (calcium-dependent) lectin-like receptors, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC1B (also known as CLEC-2) is a C-type lectin-like receptor expressed in myeloid cells and NK cells. CLEC1B acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. It also acts as a receptor for the platelet-aggregating snake venom protein rhodocytin.Synonyms: C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2, CLEC2