ROBO3
Reaktivität: Human
ELISA, WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Peptide ELISA: 1/32000. Western Blot: 0.5 - 1 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Roundabout proteins 1-3, known as Robo1-3, are repulsive axon guidance receptors that bind to Slit, a repellent secreted by midline glia during development. Robo3 (also known as Rig1) is important for normal axon navigation at the ventral midline of the neural tube during development and is specifically expressed by commissural axons in rodents. Loss-of-function studies in mice show that Robo3 is required to allow commissural axons to enter the floor plate and cross to the contralateral side of the spinal cord. Some isoforms of Robo3 exist.Synonyms: ROBO-3, Roundabout homolog 3, Roundabout-like protein 3