RAE1 Antikörper (C-Term)
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- Target Alle RAE1 Antikörper anzeigen
- RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAE1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequenz
- C-NAAEELKPRN KK
- Spezifität
- This antibody recognizes RAE1.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Porcine, Bovine.
Species reactivity (tested):Human. - Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide with sequence from the C Terminus of Human RAE1 Genename: RAE1
- Top Product
- Discover our top product RAE1 Primärantikörper
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- Applikationshinweise
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Peptide ELISA: Detection Limit: 1/64000. Western Blot: 0.03-0.1 μg/mL. Detects a band of Approx 38-40 kDa in lysates of HumanHepatocarcinoma cell line HepG2.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
- Andere Bezeichnung
- RAE1 (RAE1 Produkte)
- Synonyme
- gle2 antikoerper, mig14 antikoerper, mnrp41 antikoerper, mrnp41 antikoerper, MRNP41 antikoerper, zgc:56449 antikoerper, zgc:77723 antikoerper, 3230401I12Rik antikoerper, 41 antikoerper, D2Ertd342e antikoerper, MNRP antikoerper, MNRP41 antikoerper, MIG14 antikoerper, Mnrp41 antikoerper, dJ481F12.3 antikoerper, dJ800J21.1 antikoerper, ribonucleic acid export 1 antikoerper, RAE1 RNA export 1 homolog antikoerper, ribonucleic acid export 1 L homeolog antikoerper, rae1 antikoerper, LOC664096 antikoerper, RAE1 antikoerper, rae1.L antikoerper, Rae1 antikoerper
- Hintergrund
- Mutations in Rae1 and Gle2 (Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly. Alternatively spliced transcript variants encoding the same protein have been found for this gene.Synonyms: MRNP41, mRNA export factor, mRNA-associated protein mrnp 41
- Gen-ID
- 8480, 9606
- UniProt
- P78406
- Pathways
- SARS-CoV-2 Protein Interaktom
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