CLIC5 Antikörper (Isoform 1)

Produktnummer ABIN5540213

Produktdetails anti-CLIC5 Antikörper

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Bindungsspezifität: AA 160-173, Isoform 1

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLIC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Spezifität: This antibody recognizes CLIC5a, a 32 kDa protein which is component of actin complexes. Cross reactivity with CLIC5b was not determined.

Aufreinigung: Protein-A affinity chromatography (> 95% by SDS-PAGE)

Immunogen: KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a

Klon: CLIC5-02

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow cytometry. Western blot.

Protokoll: 1. Wegner B, Al-Momany A, Kulak SC, Kozlowski K, Obeidat M, Jahroudi N, Paes J, Berryman M, Ballermann BJ: CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity. Am J Physiol Renal Physiol. 2010 Jun298(6):F1492-503.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 95 % by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CLIC5

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Andere Bezeichnung: clic5 (CLIC5 Produkte)

Synonyme: MST130 antikoerper, MSTP130 antikoerper, 5730531E12Rik antikoerper, B330005L24 antikoerper, Gm322 antikoerper, jbg antikoerper, clic5 antikoerper, im:6907594 antikoerper, zgc:77538 antikoerper, CLIC5 antikoerper, zgc:101827 antikoerper, chloride intracellular channel 5 antikoerper, chloride intracellular channel 5b antikoerper, chloride intracellular channel 5a antikoerper, chloride intracellular channel 5 L homeolog antikoerper, CLIC5 antikoerper, Clic5 antikoerper, clic5b antikoerper, clic5a antikoerper, clic5.L antikoerper

Hintergrund: CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids). These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.

UniProt: Q9NZA1

Pathways: Sensory Perception of Sound