This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This BLOC1S3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-202 amino acids from the C-terminal region of human BLOC1S3.
BLOC1S3
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
BLOC1S3
(Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))
BLOS3 antikoerper, HPS8 antikoerper, RP antikoerper, BC043666 antikoerper, Blos3 antikoerper, E230011O18 antikoerper, rp antikoerper, biogenesis of lysosomal organelles complex 1 subunit 3 antikoerper, biogenesis of lysosomal organelles complex-1, subunit 3 antikoerper, BLOC1S3 antikoerper, Bloc1s3 antikoerper
Hintergrund
This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.