BLOC1S3 Antikörper (C-Term)
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- Target Alle BLOC1S3 Antikörper anzeigen
- BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))
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Bindungsspezifität
- AA 176-202, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BLOC1S3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This BLOC1S3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-202 amino acids from the C-terminal region of human BLOC1S3.
- Klon
- RB41728
- Isotyp
- Ig Fraction
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Genome-wide analysis of genetic loci associated with Alzheimer disease." in: JAMA : the journal of the American Medical Association, Vol. 303, Issue 18, pp. 1832-40, (2010) (PubMed).
: "A germline mutation in BLOC1S3/reduced pigmentation causes a novel variant of Hermansky-Pudlak syndrome (HPS8)." in: American journal of human genetics, Vol. 78, Issue 1, pp. 160-6, (2005) (PubMed).
: "Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28393-401, (2004) (PubMed).
: "
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Genome-wide analysis of genetic loci associated with Alzheimer disease." in: JAMA : the journal of the American Medical Association, Vol. 303, Issue 18, pp. 1832-40, (2010) (PubMed).
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- Target
- BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))
- Andere Bezeichnung
- BLOC1S3 (BLOC1S3 Produkte)
- Synonyme
- BLOS3 antikoerper, HPS8 antikoerper, RP antikoerper, BC043666 antikoerper, Blos3 antikoerper, E230011O18 antikoerper, rp antikoerper, biogenesis of lysosomal organelles complex 1 subunit 3 antikoerper, biogenesis of lysosomal organelles complex-1, subunit 3 antikoerper, BLOC1S3 antikoerper, Bloc1s3 antikoerper
- Hintergrund
- This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.
- Molekulargewicht
- 21256
- NCBI Accession
- NP_997715
- UniProt
- Q6QNY0
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