PAAF1 Antikörper (N-Term)

Produktnummer ABIN5538344

Produktdetails anti-PAAF1 Antikörper

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Bindungsspezifität: AA 109-138, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PAAF1

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Andere Bezeichnung: PAAF1 (PAAF1 Produkte)

Synonyme: paaf antikoerper, rpn14 antikoerper, wdr71 antikoerper, WDR71 antikoerper, MGC146521 antikoerper, PAAF antikoerper, Rpn14 antikoerper, proteasomal ATPase associated factor 1 S homeolog antikoerper, proteasomal ATPase associated factor 1 antikoerper, paaf1.S antikoerper, PAAF1 antikoerper, paaf1 antikoerper, Paaf1 antikoerper

Hintergrund: PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

Molekulargewicht: 42 kDa

Gen-ID: 80227

UniProt: Q9BRP4