PAAF1 Antikörper (N-Term)

Produktnummer ABIN651253

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PAAF1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PAAF1 Antikörper (N-Term) (ABIN651253)

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB25789

Produktdetails anti-PAAF1 Antikörper

Bindungsspezifität: AA 109-138, N-Term

Homologie: B

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PAAF1

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Andere Bezeichnung: PAAF1

Hintergrund: PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

Molekulargewicht: 42190

Gen-ID: 80227

NCBI Accession: NP_001254732, NP_001254733, NP_001254734, NP_001254735, NP_079431

UniProt: Q9BRP4