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PAAF1 Antikörper (N-Term)

PAAF1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB25789 unconjugated
Produktnummer ABIN651253
  • Target Alle PAAF1 Antikörper anzeigen
    PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 1
    AA 109-138, N-Term
    Reaktivität
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 16
    • 1
    Kaninchen
    Klonalität
    • 16
    • 1
    Polyklonal
    Konjugat
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PAAF1 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 14
    • 13
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.
    Klon
    RB25789
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))
    Andere Bezeichnung
    PAAF1 (PAAF1 Produkte)
    Synonyme
    paaf antikoerper, rpn14 antikoerper, wdr71 antikoerper, WDR71 antikoerper, MGC146521 antikoerper, PAAF antikoerper, Rpn14 antikoerper, proteasomal ATPase associated factor 1 S homeolog antikoerper, proteasomal ATPase associated factor 1 antikoerper, paaf1.S antikoerper, PAAF1 antikoerper, paaf1 antikoerper, Paaf1 antikoerper
    Hintergrund
    PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
    Molekulargewicht
    42190
    Gen-ID
    80227
    NCBI Accession
    NP_001254732, NP_001254733, NP_001254734, NP_001254735, NP_079431
    UniProt
    Q9BRP4
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