PDE8B Antikörper (AA 296-324)

Produktnummer ABIN5538156

Produktdetails anti-PDE8B Antikörper

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Bindungsspezifität: AA 296-324

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PDE8B

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Andere Bezeichnung: PDE8B (PDE8B Produkte)

Synonyme: PDE8B antikoerper, ADSD antikoerper, PPNAD3 antikoerper, B230331L10Rik antikoerper, C030047E14Rik antikoerper, RNPDE8B antikoerper, phosphodiesterase 8B antikoerper, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antikoerper, PDE8B antikoerper, LOC100468338 antikoerper, pde8b antikoerper, Pde8b antikoerper

Hintergrund: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 99 kDa

Gen-ID: 8622

UniProt: O95263

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process