This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PTPRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the N-terminal region of human PTPRN2.
PTPRN2
Reaktivität: Human
WB, IHC, ICC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
PTPRN2
(Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2))
IA-2beta antikoerper, IAR antikoerper, ICAAR antikoerper, PTPRP antikoerper, R-PTP-N2 antikoerper, 4930425H11Rik antikoerper, IA2beta antikoerper, PTP-NP antikoerper, Phol antikoerper, mKIAA0387 antikoerper, phogrin antikoerper, protein tyrosine phosphatase, receptor type N2 antikoerper, protein tyrosine phosphatase, receptor type, N polypeptide 2 antikoerper, PTPRN2 antikoerper, Ptprn2 antikoerper
Hintergrund
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.