RND3 Antikörper (AA 133-165)

Produktnummer ABIN5537459

Produktdetails anti-RND3 Antikörper

Target: RND3 (rho Family GTPase 3 (RND3))

Bindungsspezifität: AA 133-165

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RND3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This ARHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Andere Bezeichnung: ARHE (RND3 Produkte)

Synonyme: ARHE antikoerper, Rho8 antikoerper, RhoE antikoerper, memB antikoerper, MGC83857 antikoerper, 2610017M01Rik antikoerper, AI661404 antikoerper, Arhe antikoerper, Rhoe antikoerper, RHOE antikoerper, arhe antikoerper, id:ibd2712 antikoerper, id:ibd2919 antikoerper, rho8 antikoerper, rnd3 antikoerper, wu:fc39h07 antikoerper, zgc:73080 antikoerper, wu:fd06e12 antikoerper, zgc:92324 antikoerper, Rho family GTPase 3 antikoerper, Rho family GTPase 3 L homeolog antikoerper, Rho family GTPase 3a antikoerper, Rho family GTPase 3b antikoerper, RND3 antikoerper, rnd3.L antikoerper, Rnd3 antikoerper, rnd3a antikoerper, rnd3b antikoerper

Hintergrund: Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925), GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855), and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).

Molekulargewicht: 27 kDa

Gen-ID: 390

UniProt: P61587