Presenilin 2 Antikörper (N-Term)
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- Target Alle Presenilin 2 (PSEN2) Antikörper anzeigen
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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Bindungsspezifität
- AA 32-65, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Presenilin 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PSEN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from the N-terminal region of human PSEN2(Presenilin-2 NTF subunit).
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PSEN2 Primärantikörper
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- Applikationshinweise
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For FACS starting dilution is: 1:25
For WB starting dilution is: 1:1000 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
- Andere Bezeichnung
- PSEN2 (PSEN2 Produkte)
- Synonyme
- AD3L antikoerper, AD4 antikoerper, CMD1V antikoerper, PS2 antikoerper, STM2 antikoerper, ALG-3 antikoerper, Ad4h antikoerper, Alg3 antikoerper, PS-2 antikoerper, Psnl2 antikoerper, pre2 antikoerper, zf-PS2 antikoerper, PSNL2 antikoerper, PSEN2 antikoerper, ad4 antikoerper, ps2 antikoerper, ad3l antikoerper, stm2 antikoerper, Ps2 antikoerper, presenilin 2 antikoerper, presenilin 2 S homeolog antikoerper, presenilin 2 (Alzheimer disease 4) antikoerper, trefoil factor 1 antikoerper, PSEN2 antikoerper, Psen2 antikoerper, psen2 antikoerper, psen2.S antikoerper, Tff1 antikoerper
- Hintergrund
- Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
- Molekulargewicht
- 50 kDa
- Gen-ID
- 5664
- UniProt
- P49810
- Pathways
- Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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