This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.
MLLT1
Reaktivität: Human
IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
MLLT1
(MLLT1, super elongation complex subunit (MLLT1))
MGC84026 antikoerper, MLLT1 antikoerper, ENL antikoerper, LTG19 antikoerper, YEATS1 antikoerper, AA407901 antikoerper, BAM11 antikoerper, MLLT1, super elongation complex subunit antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 antikoerper, Mllt1 antikoerper, MLLT1 antikoerper, mllt1.L antikoerper, mllt1 antikoerper
Hintergrund
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.