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MLLT1 Antikörper (C-Term)

MLLT1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB1927-1928 unconjugated
Produktnummer ABIN390126
  • Target Alle MLLT1 Antikörper anzeigen
    MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 523-552, C-Term
    Reaktivität
    • 29
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    • 3
    Kaninchen
    Klonalität
    • 27
    • 2
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    Dieser MLLT1 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 17
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.
    Klon
    RB1927-1928
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:2000. WB: 1:2000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Bitoun, Oliver, Davies: "The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling." in: Human molecular genetics, Vol. 16, Issue 1, pp. 92-106, (2007) (PubMed).

  • Target
    MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
    Andere Bezeichnung
    MLLT1 (MLLT1 Produkte)
    Synonyme
    MGC84026 antikoerper, MLLT1 antikoerper, ENL antikoerper, LTG19 antikoerper, YEATS1 antikoerper, AA407901 antikoerper, BAM11 antikoerper, MLLT1, super elongation complex subunit antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 antikoerper, Mllt1 antikoerper, MLLT1 antikoerper, mllt1.L antikoerper, mllt1 antikoerper
    Hintergrund
    Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
    Molekulargewicht
    62056
    Gen-ID
    4298
    NCBI Accession
    NP_005925
    UniProt
    Q03111
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