MAPK15 Antikörper (N-Term)

Produktnummer ABIN5536093

Produktdetails anti-MAPK15 Antikörper

Target: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Bindungsspezifität: AA 32-61, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This MAPK15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human MAPK15.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MAPK15

Target: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Andere Bezeichnung: MAPK15 (MAPK15 Produkte)

Synonyme: MGC138052 antikoerper, MGC99048 antikoerper, erk7 antikoerper, zgc:110345 antikoerper, ERK7 antikoerper, ERK8 antikoerper, BC048082 antikoerper, Erk7 antikoerper, ATMPK15 antikoerper, F25P22.9 antikoerper, F25P22_9 antikoerper, MAP kinase 15 antikoerper, mitogen-activated protein kinase 15 antikoerper, mitogen-activated protein kinase 15 L homeolog antikoerper, MAP kinase 15 antikoerper, MAPK15 antikoerper, mapk15.L antikoerper, mapk15 antikoerper, Tsp_00300 antikoerper, Mapk15 antikoerper, MPK15 antikoerper

Hintergrund: The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.

Molekulargewicht: 60 kDa

Gen-ID: 225689

UniProt: Q8TD08