APIP Antikörper (AA 111-142)

Produktnummer ABIN5535618

Produktdetails anti-APIP Antikörper

Target: APIP (APAF1 Interacting Protein (APIP))

Bindungsspezifität: AA 111-142

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APIP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 111-142 amino acids from the Central region of human APIP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu APIP

Target: APIP (APAF1 Interacting Protein (APIP))

Andere Bezeichnung: APIP (APIP Produkte)

Synonyme: APIP2 antikoerper, CGI29 antikoerper, MMRP19 antikoerper, dJ179L10.2 antikoerper, hAPIP antikoerper, CGI-29 antikoerper, Mmrp19 antikoerper, RGD1564562 antikoerper, zgc:103619 antikoerper, APAF1 interacting protein antikoerper, APAF1 interacting protein S homeolog antikoerper, APIP antikoerper, Apip antikoerper, apip antikoerper, apip.S antikoerper

Hintergrund: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Molekulargewicht: 27 kDa

Gen-ID: 51074

UniProt: Q96GX9

Pathways: Methionine Biosynthetic Process