MERTK Antikörper

Produktnummer ABIN5534530

Produktdetails anti-MERTK Antikörper

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MERTK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This MERTK antibody is generated from rabbits immunized with a his tag recombinant protein of human MERTK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

For IHC-P starting dilution is: 1:50~10

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MERTK

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Andere Bezeichnung: MERTK (MERTK Produkte)

Synonyme: MER antikoerper, RP38 antikoerper, c-mer antikoerper, Eyk antikoerper, Mer antikoerper, Nyk antikoerper, nmf12 antikoerper, rdy antikoerper, C-EYK antikoerper, MERTK antikoerper, DKFZp469D2215 antikoerper, si:ch1073-268l12.2 antikoerper, MER proto-oncogene, tyrosine kinase antikoerper, c-mer proto-oncogene tyrosine kinase antikoerper, c-mer proto-oncogene tyrosine kinase a antikoerper, MERTK antikoerper, Mertk antikoerper, mertka antikoerper

Hintergrund: MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Molekulargewicht: 110 kDa

Gen-ID: 10461

UniProt: Q12866

Pathways: RTK Signalweg