This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogen
This CYP7A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human CYP7A1.
CYP7A1
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
CYP7A1
(Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
CP7A antikoerper, CYP7 antikoerper, CYPVII antikoerper, CHAP antikoerper, CYP7S1 antikoerper, cyp7a1a antikoerper, zgc:63920 antikoerper, cytochrome P450 family 7 subfamily A member 1 antikoerper, cytochrome P450, family 7, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 7, subfamily A, polypeptide 1 antikoerper, cholesterol 7-alpha-hydroxylase antikoerper, CYP7A1 antikoerper, Cyp7a1 antikoerper, cyp7a1 antikoerper
Hintergrund
CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.