This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogen
This CYP2C8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-105 amino acids from the N-terminal region of human CYP2C8.
CYP2C8
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
CYP2C8
(Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))
CPC8 antikoerper, CYPIIC8 antikoerper, MP-12/MP-20 antikoerper, CYP2C74 antikoerper, cpc8 antikoerper, cyp2c8 antikoerper, cypiic8 antikoerper, mp-12/mp-20 antikoerper, cytochrome P450 family 2 subfamily C member 8 antikoerper, Cytochrome P450 2C8 antikoerper, cytochrome P450, family 2, subfamily C, polypeptide 8 antikoerper, cytochrome P450 family 2 subfamily C member 8 S homeolog antikoerper, CYP2C8 antikoerper, CTN_0597 antikoerper, cyp2c8.1.S antikoerper, cyp2c8.1 antikoerper
Hintergrund
CYP2C8 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol.