CYP21A2 Antikörper (AA 216-246)

Produktnummer ABIN5534023

Produktdetails anti-CYP21A2 Antikörper

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Bindungsspezifität: AA 216-246

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP21A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This CYP21A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-246 amino acids from the Central region of human CYP21A2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CYP21A2

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Andere Bezeichnung: CYP21A2 (CYP21A2 Produkte)

Synonyme: CA21H antikoerper, CAH1 antikoerper, CPS1 antikoerper, CYP21 antikoerper, CYP21B antikoerper, P450c21B antikoerper, 21-OH antikoerper, 21OH antikoerper, 21OHA antikoerper, 21OHB antikoerper, CYP21OH-A antikoerper, Cyp21 antikoerper, Cyp21-ps1 antikoerper, Cyp21B antikoerper, Cyp21a2-ps antikoerper, Cyp21a2ps antikoerper, Oh21-1 antikoerper, Oh21-2 antikoerper, CYP21A antikoerper, 21-OHase antikoerper, cytochrome P450 family 21 subfamily A member 2 antikoerper, cytochrome P450, family 21, subfamily a, polypeptide 1 antikoerper, cytochrome P450c21 antikoerper, cytochrome P450, family 21, subfamily A, polypepide 2 antikoerper, cytochrome P450, family 21, subfamily A, polypeptide 2 antikoerper, steroid 21-hydroxylase-like antikoerper, CYP21A2 antikoerper, Cyp21a1 antikoerper, LOC101094596 antikoerper

Hintergrund: CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in CYP21A2 gene cause congenital adrenal hyperplasia.

Molekulargewicht: 56 kDa

Gen-ID: 1589

UniProt: P08686

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process