CYP21A2 Antikörper (C-Term)
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- Target Alle CYP21A2 Antikörper anzeigen
- CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Rind (Kuh), Hund, Meerschweinchen, Schwein, Schaf
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP21A2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- IQQRLQEELD HELGPGASSS RVPYKDRARL PLLNATIAEV LRLRPVVPLA
- Homologie
- Cow: 92%, Dog: 92%, Guinea Pig: 80%, Human: 100%, Pig: 92%, Sheep: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CYP21A2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CYP21A2
- Top Product
- Discover our top product CYP21A2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 495 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
- Andere Bezeichnung
- CYP21A2 (CYP21A2 Produkte)
- Synonyme
- CA21H antikoerper, CAH1 antikoerper, CPS1 antikoerper, CYP21 antikoerper, CYP21B antikoerper, P450c21B antikoerper, 21-OH antikoerper, 21OH antikoerper, 21OHA antikoerper, 21OHB antikoerper, CYP21OH-A antikoerper, Cyp21 antikoerper, Cyp21-ps1 antikoerper, Cyp21B antikoerper, Cyp21a2-ps antikoerper, Cyp21a2ps antikoerper, Oh21-1 antikoerper, Oh21-2 antikoerper, CYP21A antikoerper, 21-OHase antikoerper, cytochrome P450 family 21 subfamily A member 2 antikoerper, cytochrome P450, family 21, subfamily a, polypeptide 1 antikoerper, cytochrome P450c21 antikoerper, cytochrome P450, family 21, subfamily A, polypepide 2 antikoerper, cytochrome P450, family 21, subfamily A, polypeptide 2 antikoerper, steroid 21-hydroxylase-like antikoerper, CYP21A2 antikoerper, Cyp21a1 antikoerper, LOC101094596 antikoerper
- Hintergrund
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene, gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CA21H, CAH1, CPS1, CYP21, CYP21B, MGC150536, MGC150537, P450c21B
Protein Size: 495 - Molekulargewicht
- 56 kDa
- Gen-ID
- 1589
- NCBI Accession
- NM_000500, NP_000491
- UniProt
- Q16874
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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