RGS19 Antikörper (AA 131-156)

Produktnummer ABIN5533774

Produktdetails anti-RGS19 Antikörper

Target: RGS19 (Regulator of G-Protein Signalling 19 (RGS19))

Bindungsspezifität: AA 131-156

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-156 amino acids from human RGS19.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RGS19

Target: RGS19 (Regulator of G-Protein Signalling 19 (RGS19))

Andere Bezeichnung: RGS19 (RGS19 Produkte)

Synonyme: RGS19 antikoerper, GAIP antikoerper, RGSGAIP antikoerper, 2610042F04Rik antikoerper, AI324841 antikoerper, AW547781 antikoerper, Camki antikoerper, Gaip antikoerper, regulator of G protein signaling 19 antikoerper, regulator of G-protein signaling 19 antikoerper, RGS19 antikoerper, Rgs19 antikoerper

Hintergrund: RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

Molekulargewicht: 25 kDa

Gen-ID: 10287

UniProt: P49795

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling