ATF6B Antikörper (C-Term)

Produktnummer ABIN5533737

Produktdetails anti-ATF6B Antikörper

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Bindungsspezifität: AA 560-589, C-Term

Reaktivität: Human, Maus, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ATF6B

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Andere Bezeichnung: CREBL1 (ATF6B Produkte)

Synonyme: CREBL1 antikoerper, CREB-RP antikoerper, G13 antikoerper, AA617266 antikoerper, ATF6beta antikoerper, Creb-rp antikoerper, Crebl1 antikoerper, activating transcription factor 6 beta antikoerper, cyclic AMP-dependent transcription factor ATF-6 beta antikoerper, ATF6B antikoerper, LOC745411 antikoerper, Atf6b antikoerper

Hintergrund: CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

Molekulargewicht: 77 kDa

Gen-ID: 1388

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction