ARHGEF7 Antikörper (AA 654-688)

Produktnummer ABIN5532990

Produktdetails anti-ARHGEF7 Antikörper

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Bindungsspezifität: AA 654-688

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGEF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 654-688 amino acids from human ARHGEF7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Andere Bezeichnung: ARHGEF7 (ARHGEF7 Produkte)

Synonyme: BETA-PIX antikoerper, COOL-1 antikoerper, COOL1 antikoerper, Nbla10314 antikoerper, P50 antikoerper, P50BP antikoerper, P85 antikoerper, P85COOL1 antikoerper, P85SPR antikoerper, PAK3 antikoerper, PIXB antikoerper, cool1 antikoerper, p50 antikoerper, p85 antikoerper, pak3 antikoerper, pixb antikoerper, ARHGEF7 antikoerper, P85spr antikoerper, Pak3bp antikoerper, Cool antikoerper, PIX antikoerper, betaPix antikoerper, betaPix-b antikoerper, betaPix-c antikoerper, cool-1 antikoerper, mKIAA0142 antikoerper, p85Cool1 antikoerper, p85SPR antikoerper, arhgef7 antikoerper, bbh antikoerper, bpix antikoerper, im:7142367 antikoerper, wu:fc35h08 antikoerper, zgc:101775 antikoerper, Rho guanine nucleotide exchange factor 7 antikoerper, Rho guanine nucleotide exchange factor 7 S homeolog antikoerper, ankyrin repeat domain 10 antikoerper, Rho guanine nucleotide exchange factor (GEF7) antikoerper, Rho guanine nucleotide exchange factor (GEF) 7b antikoerper, ARHGEF7 antikoerper, arhgef7.S antikoerper, arhgef7 antikoerper, ANKRD10 antikoerper, Arhgef7 antikoerper, arhgef7b antikoerper

Hintergrund: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Molekulargewicht: 90 kDa

Gen-ID: 8874

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation