ARHGEF7 Antikörper
Kurzübersicht für ARHGEF7 Antikörper (ABIN1169227)
Target
Alle ARHGEF7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms.
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Kreuzreaktivität (Details)
- Cross-reacts with human and rat beta-Pix.
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Sterilität
- 0.2 μm filtered
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Immunogen
- Recombinant beta-Pix SH3 domain.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Haltbarkeit
- 6 months
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: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).
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- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
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Andere Bezeichnung
- beta-Pix
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Hintergrund
- Beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
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UniProt
- Q9ES28
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation
Target
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