ARHGEF7 Antikörper

Produktnummer ABIN1169227

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ARHGEF7 in WB, ELISA und ICC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.Es wurde in 1 Publikation zitiert.

Kurzübersicht für ARHGEF7 Antikörper (ABIN1169227)

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-ARHGEF7 Antikörper

Verwendungszweck: anti-beta-Pix (mouse), pAb

Spezifität: Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix.

Kreuzreaktivität (Details): Cross-reacts with human and rat beta-Pix.

Produktmerkmale: Polyclonal Antibody. Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix. Source: Rabbit. Applications: ELISA, ICC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant beta-Pix SH3 domain.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Referenzen für anti-ARHGEF7 Antikörper (ABIN1169227)

Oh, Yoo, Jo, Song, Kim, Park: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).

Details zu ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Andere Bezeichnung: beta-Pix

Hintergrund:

Alternate Names/Synonyms: ARHGEF7, Rho Guanine Nucleotide Exchange Factor 7, PAK-interacting Exchange Factor beta, p85SPR, COOL-1

Product Description: beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.

UniProt: Q9ES28

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation