Cadherin 5 Antikörper (N-Term)

Produktnummer ABIN5532854

Produktdetails anti-Cadherin 5 Antikörper

Target: Cadherin 5 (CDH5)

Bindungsspezifität: AA 106-134, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VE Cadherin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human VE Cadherin.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For FACS starting dilution is: 1:25

For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: VE Cadherin (CDH5 Produkte)

Synonyme: 7B4 antikoerper, AA408225 antikoerper, Cd144 antikoerper, VE-Cad antikoerper, VECD antikoerper, VEcad antikoerper, Vec antikoerper, wu:fc88a07 antikoerper, CD144 antikoerper, cadherin-5 antikoerper, cadherin 5 antikoerper, CDH5 antikoerper, Cdh5 antikoerper, cdh5 antikoerper

Hintergrund: CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.

Molekulargewicht: 88 kDa

Gen-ID: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2