RNF14 Antikörper (C-Term)

Produktnummer ABIN5532712

Produktdetails anti-RNF14 Antikörper

Target: RNF14 (Ring Finger Protein 14 (RNF14))

Bindungsspezifität: AA 336-364, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the C-terminal region of human RNF14.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RNF14

Target: RNF14 (Ring Finger Protein 14 (RNF14))

Andere Bezeichnung: RNF14 (RNF14 Produkte)

Synonyme: ARA54 antikoerper, HFB30 antikoerper, TRIAD2 antikoerper, 2310075C09Rik antikoerper, 2610005D23Rik antikoerper, AA986456 antikoerper, AU041447 antikoerper, D18Ertd188e antikoerper, D7Bwg0165e antikoerper, Triad2 antikoerper, ring finger protein 14 antikoerper, RNF14 antikoerper, Rnf14 antikoerper

Hintergrund: The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Molekulargewicht: 54 kDa

Gen-ID: 9604

UniProt: Q9UBS8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling