SEPN1 Antikörper (C-Term)

Produktnummer ABIN5532164

Produktdetails anti-SEPN1 Antikörper

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Bindungsspezifität: AA 417-445, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEPN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human SEPN1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SEPN1

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Andere Bezeichnung: SEPN1 (SEPN1 Produkte)

Synonyme: CFTD antikoerper, MDRS1 antikoerper, RSMD1 antikoerper, RSS antikoerper, SELN antikoerper, 1110019I12Rik antikoerper, AI414492 antikoerper, SePN antikoerper, cb686 antikoerper, wu:fb06g01 antikoerper, wu:fb73d02 antikoerper, wu:fv41b08 antikoerper, zgc:101091 antikoerper, selenoprotein N antikoerper, SELENON antikoerper, Selenon antikoerper, selenon antikoerper

Hintergrund: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht: 66 kDa

Gen-ID: 57190

UniProt: Q9NZV5

Pathways: Skeletal Muscle Fiber Development