Prohibitin 2 Antikörper (AA 225-255)

Produktnummer ABIN5531959

Produktdetails anti-Prohibitin 2 Antikörper

Target: Prohibitin 2 (PHB2)

Bindungsspezifität: AA 225-255

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prohibitin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PHB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from human PHB2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Prohibitin 2

Target: Prohibitin 2 (PHB2)

Andere Bezeichnung: PHB2 (PHB2 Produkte)

Synonyme: bcap37 antikoerper, zgc:73150 antikoerper, wu:fc28c08 antikoerper, PHB2 antikoerper, phb2 antikoerper, ATPHB2 antikoerper, F21M11.21 antikoerper, F21M11_21 antikoerper, prohibitin 2 antikoerper, DKFZp469N1310 antikoerper, BAP antikoerper, BCAP37 antikoerper, Bap37 antikoerper, PNAS-141 antikoerper, REA antikoerper, p22 antikoerper, bap37 antikoerper, prohibitin2 antikoerper, xphb2 antikoerper, AU044498 antikoerper, Bcap37 antikoerper, Bap antikoerper, Bap-37 antikoerper, Bcap27 antikoerper, prohibitin 2a antikoerper, prohibitin 2 antikoerper, prohibitin 2 S homeolog antikoerper, phb2a antikoerper, PHB2 antikoerper, phb2 antikoerper, phb2.S antikoerper, Phb2 antikoerper

Hintergrund: PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.

Molekulargewicht: 33 kDa

Gen-ID: 11331

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling