Prohibitin 2 Antikörper (C-Term)

Produktnummer ABIN2783329

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Prohibitin 2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Hund und Schwein.

Kurzübersicht für Prohibitin 2 Antikörper (C-Term) (ABIN2783329)

Target: Prohibitin 2 (PHB2)

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prohibitin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Prohibitin 2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PHB2 Antibody - C-terminal region

Sequenz: KLRKIRAAQN ISKTIATSQN RIYLTADNLV LNLQDESFTR GSDSLIKGKK

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHB2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108959

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Prohibitin 2

Target: Prohibitin 2 (PHB2)

Andere Bezeichnung: PHB2

Hintergrund:

Background Information: PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.

Gene Name: Prohibitin 2

Alternative Symbols: BAP, REA, p22, hBAP, Bap37, BCAP37, PNAS-141

Protein Name: Prohibitin-2

Molekulargewicht: 33kDa

Gen-ID: 11331

NCBI Accession: NP_009204

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling