PFN1 Antikörper (AA 108-140)

Produktnummer ABIN5531819

Produktdetails anti-PFN1 Antikörper

Target: PFN1 (Profilin 1 (PFN1))

Bindungsspezifität: AA 108-140

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Profilin-1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-140 amino acids from the human region of human Profilin-1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For FACS starting dilution is: 1:25

For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PFN1

Target: PFN1 (Profilin 1 (PFN1))

Andere Bezeichnung: Profilin-1 (PFN1 Produkte)

Synonyme: GmPRO1 antikoerper, GmPRO2 antikoerper, PRO1 antikoerper, Profilin-1 antikoerper, profilin-1 antikoerper, profilin antikoerper, MGC130883 antikoerper, Profilin1 antikoerper, XProfilin1 antikoerper, sb:cb813 antikoerper, wu:fa91a03 antikoerper, ALS18 antikoerper, Pfn antikoerper, F6F22.21 antikoerper, F6F22_21 antikoerper, PFN1 antikoerper, PROFILIN 1 antikoerper, profilin 1 antikoerper, profilin antikoerper, profilin 1 antikoerper, profilin 1 L homeolog antikoerper, profilin homolog 1 antikoerper, Profilin-1 antikoerper, PRO2 antikoerper, PFN1 antikoerper, pfn1.L antikoerper, pfn1 antikoerper, Pfn1 antikoerper, PRF1 antikoerper, prf1 antikoerper, pfn-1 antikoerper

Hintergrund: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Molekulargewicht: 15 kDa

Gen-ID: 5216

UniProt: P07737

Pathways: Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location